Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50376570
Substrate
n/a
Meas. Tech.
ChEMBL_477389 (CHEMBL928177)
EC50
0.8±n/a nM
Citation
 Verbist, BM; De Cleyn, MA; Surkyn, M; Fraiponts, E; Aerssens, J; Nijsen, MJ; Gijsen, HJ 5-Sulfonyl-benzimidazoles as selective CB2 agonists. Bioorg Med Chem Lett 18:2574-9 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50376570
Synonyms:
CHEMBL261347
Type:
Small organic molecule
Emp. Form.:
C22H26FN3O3S
Mol. Mass.:
431.524
SMILES:
CC(C)(C)c1nc2cc(ccc2n1CC1CCOCC1)S(=O)(=O)c1ccnc(F)c1
Structure:
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