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Target
IAG-nucleoside hydrolase
Ligand
BDBM50260488
Substrate
n/a
Meas. Tech.
ChEMBL_531315 (CHEMBL989727)
Ki
685000±n/a nM
Citation
 Goeminne, A; McNaughton, M; Bal, G; Surpateanu, G; Van Der Veken, P; De Prol, S; Versées, W; Steyaert, J; Haemers, A; Augustyns, K Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors. Eur J Med Chem 43:315-26 (2008) [PubMed]  Article 
Target
Name:
IAG-nucleoside hydrolase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
36316.77
Organism:
Trypanosoma vivax
Description:
ChEMBL_531315
Residue:
327
Sequence:
MAKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMCTHCELLRDGDGYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAEKYPLTFVARNPEAEFFLDMLLRSARAC
  
Inhibitor
Name:
BDBM50260488
Synonyms:
2-Guanidino-4,7-anhydro-1,2,3-trideoxy-Dallo-octitol | CHEMBL450920
Type:
Small organic molecule
Emp. Form.:
C9H19N3O4
Mol. Mass.:
233.2649
SMILES:
[#6]-[#6](-[#6]-[#6@@H]-1-[#8]-[#6@H](-[#6]-[#8])-[#6@@H](-[#8])-[#6@H]-1-[#8])\[#7]=[#6](\[#7])-[#7] |r|
Structure:
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