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Target
IAG-nucleoside hydrolase
Ligand
BDBM50260496
Substrate
n/a
Meas. Tech.
ChEMBL_531315 (CHEMBL989727)
Ki
7000±n/a nM
Citation
 Goeminne, A; McNaughton, M; Bal, G; Surpateanu, G; Van Der Veken, P; De Prol, S; Versées, W; Steyaert, J; Haemers, A; Augustyns, K Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors. Eur J Med Chem 43:315-26 (2008) [PubMed]  Article 
Target
Name:
IAG-nucleoside hydrolase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
36316.77
Organism:
Trypanosoma vivax
Description:
ChEMBL_531315
Residue:
327
Sequence:
MAKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMCTHCELLRDGDGYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAEKYPLTFVARNPEAEFFLDMLLRSARAC
  
Inhibitor
Name:
BDBM50260496
Synonyms:
1,4-Dideoxy-1,4-imino-N-(4-guanidinobenzyl)-D-ribitol | CHEMBL505234
Type:
Small organic molecule
Emp. Form.:
C13H20N4O3
Mol. Mass.:
280.3229
SMILES:
[#7]\[#6](-[#7])=[#7]\c1ccc(-[#6]-[#7]-2-[#6]-[#6@H](-[#8])-[#6@H](-[#8])-[#6@H]-2-[#6]-[#8])cc1 |r|
Structure:
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