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Target
Galectin-7
Ligand
BDBM50273582
Substrate
n/a
Meas. Tech.
ChEMBL_560913 (CHEMBL1013548)
Kd
7600±n/a nM
Citation
 Delaine, T; Cumpstey, I; Ingrassia, L; Le Mercier, M; Okechukwu, P; Leffler, H; Kiss, R; Nilsson, UJ Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells. J Med Chem 51:8109-14 (2008) [PubMed]  Article 
Target
Name:
Galectin-7
Synonyms:
Gal-7 | HKL-14 | LEG7_HUMAN | LGALS7 | PI7 | PIG1 | p53-induced gene 1 protein
Type:
Galactoside-binding protein
Mol. Mass.:
15077.89
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
136
Sequence:
MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF
  
Inhibitor
Name:
BDBM50273582
Synonyms:
CHEMBL516152 | N-((2S,3R,4S,5R,6R)-2-((2R,3S,4R,5R,6R)-5-acetamido-4-hydroxy-2-(hydroxymethyl)-6-methoxy-tetrahydro-2H-pyran-3-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-4-yl)-1-naphthamide
Type:
Small organic molecule
Emp. Form.:
C26H34N2O11
Mol. Mass.:
550.555
SMILES:
CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](NC(=O)c3cccc4ccccc34)[C@H]2O)[C@H](O)[C@H]1NC(C)=O |r|
Structure:
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