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Target
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Ligand
BDBM50245830
Substrate
n/a
Meas. Tech.
ChEMBL_559689 (CHEMBL1010087)
IC50
46.5±n/a nM
Citation
 Alhamadsheh, MM; Waters, NC; Sachdeva, S; Lee, P; Reynolds, KA Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors. Bioorg Med Chem Lett 18:6402-5 (2008) [PubMed]  Article 
Target
Name:
Beta-ketoacyl-[acyl-carrier-protein] synthase III
Synonyms:
Beta-ketoacyl-ACP-synthase III
Type:
PROTEIN
Mol. Mass.:
42334.64
Organism:
Plasmodium falciparum
Description:
ChEMBL_559689
Residue:
371
Sequence:
MFLYFITYLCIFHNNIYSVELIKNNKYNFINNVHNIKYRTKIRAIYGKTGGKIIGHGHSYPSTEIYNDELKKYVDTNDEWIRTRTGIKKRRILKRDENISMLQIDSATQALETSCLKPSDIDMVINASSTPQNLFGDANNISNKIGCKNSVNMDLTAACTGFIFAFVTAYNFLNRYKNILIVGSDALSNFVDWRDRNTCVLFGDAAGAVVLQRTEEKEENKIFNYYLGSDSELNDLLTINFDHDKYNLDKPNVNKYGKLYMNGKEVFKYTISNIPKILKKAIQHSNINIEDINYFIFHQANIRIIETVAKNLNIPMSKVLVNLDEYANTSAASIPLCFSENIKNGKIKTNDIICMCGFGAGMSYGCVILKY
  
Inhibitor
Name:
BDBM50245830
Synonyms:
3-(1,4-dihydroxynaphthalen-2-ylsulfonyl)propanoic acid | CHEMBL455414
Type:
Small organic molecule
Emp. Form.:
C13H12O6S
Mol. Mass.:
296.296
SMILES:
OC(=O)CCS(=O)(=O)c1cc(O)c2ccccc2c1O
Structure:
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