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Target
D(2) dopamine receptor
Ligand
BDBM50107247
Substrate
n/a
Meas. Tech.
ChEMBL_496148 (CHEMBL1000137)
Ki
1220±n/a nM
Citation
 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Novel 4-(4-aryl)cyclohexyl-1-(2-pyridyl)piperazines as Delta(8)-Delta(7) sterol isomerase (emopamil binding protein) selective ligands with antiproliferative activity. J Med Chem 51:7523-31 (2009) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50107247
Synonyms:
1-(4-(3-methoxyphenyl)cyclohex-3-enyl)-4-(pyridin-2-yl)piperazine | 1-[4-(3-Methoxy-phenyl)-cyclohex-3-enyl]-4-pyridin-2-yl-piperazine | CHEMBL140287
Type:
Small organic molecule
Emp. Form.:
C22H27N3O
Mol. Mass.:
349.4693
SMILES:
COc1cccc(c1)C1=CCC(CC1)N1CCN(CC1)c1ccccn1 |t:9|
Structure:
Search PDB for entries with ligand similarity: