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Target
Carbonic anhydrase
Ligand
BDBM10872
Substrate
n/a
Meas. Tech.
ChEMBL_515851 (CHEMBL993110)
Ki
154±n/a nM
Citation
 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates. Bioorg Med Chem 17:1158-63 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
CAN_YEAST | NCE103 | NCE3
Type:
PROTEIN
Mol. Mass.:
24861.97
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_1507033
Residue:
221
Sequence:
MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK
  
Inhibitor
Name:
BDBM10872
Synonyms:
4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide | CHEMBL7146 | aromatic/heteroaromatic sulfonamide 17
Type:
Small organic molecule
Emp. Form.:
C14H17N3O4S2
Mol. Mass.:
355.432
SMILES:
Nc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O
Structure:
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