Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM50045877
Substrate
n/a
Meas. Tech.
ChEMBL_516175 (CHEMBL984215)
Ki
5±n/a nM
Citation
 Scarf, AM; Ittner, LM; Kassiou, M The translocator protein (18 kDa): central nervous system disease and drug design. J Med Chem 52:581-92 (2009) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:
Mitochondrion membrane protein
Mol. Mass.:
18945.84
Organism:
Rattus norvegicus (rat)
Description:
Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:
169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
  
Inhibitor
Name:
BDBM50045877
Synonyms:
2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylacetamide | 2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dihexyl-acetamide | CHEMBL63154 | [N,N-di-n-hexyl-2-(4-fluorophenyl) indole-3-acetamide]
Type:
Small organic molecule
Emp. Form.:
C28H37FN2O
Mol. Mass.:
436.6046
SMILES:
CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: