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Target
Carbonic anhydrase 15
Ligand
BDBM10888
Substrate
n/a
Meas. Tech.
ChEMBL_592895 (CHEMBL1048398)
Ki
634±n/a nM
Citation
 Temperini, C; Innocenti, A; Scozzafava, A; Parkkila, S; Supuran, CT The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. J Med Chem 53:850-4 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 15
Synonyms:
CAH15_MOUSE | Ca15 | Car15
Type:
PROTEIN
Mol. Mass.:
35484.02
Organism:
Mus musculus
Description:
ChEMBL_651955
Residue:
324
Sequence:
MWALDFLLSFLLIQLAAQVDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRLVQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQLHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDRDNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVLWTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSSVSTLPCLHLALVGLGVGLRLWQGP
  
Inhibitor
Name:
BDBM10888
Synonyms:
1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 | SPR_2 | US10172837, Zonisamide | Zonisamide | Zonisamide (ZNA) | Zonisamide (ZNS) | Zonisamide, 1 | Zonisamide, ZNS
Type:
Small organic molecule
Emp. Form.:
C8H8N2O3S
Mol. Mass.:
212.226
SMILES:
NS(=O)(=O)Cc1noc2ccccc12
Structure:
Search PDB for entries with ligand similarity: