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Target
Serine racemase
Ligand
BDBM50378532
Substrate
n/a
Meas. Tech.
ChEMBL_594810 (CHEMBL1042549)
IC50
370000±n/a nM
Citation
 Hoffman, HE; Jirásková, J; Cígler, P; Sanda, M; Schraml, J; Konvalinka, J Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor. J Med Chem 52:6032-41 (2009) [PubMed]  Article 
Target
Name:
Serine racemase
Synonyms:
D-serine ammonia-lyase | D-serine dehydratase | L-serine ammonia-lyase | L-serine dehydratase | SRR_MOUSE | Srr
Type:
PROTEIN
Mol. Mass.:
36355.92
Organism:
Mus musculus
Description:
ChEMBL_1441161
Residue:
339
Sequence:
MCAQYCISFADVEKAHINIQDSIHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTPEEKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYCDPSDESREKVTQRIMQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKALKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWGRMKLLIEPTAGVALAAVLSQHFQTVSPEVKNVCIVLSGGNVDLTSLNWVGQAERPAPYQTVSV
  
Inhibitor
Name:
BDBM50378532
Synonyms:
CHEMBL569435
Type:
Small organic molecule
Emp. Form.:
C3H6N2O4
Mol. Mass.:
134.0907
SMILES:
ONC(=O)CC(=O)NO
Structure:
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