Reaction Details Report a problem with these data
Target
Asialoglycoprotein receptor 1
Ligand
BDBM50077229
Substrate
n/a
Meas. Tech.
ChEMBL_603826 (CHEMBL1042966)
Kd
1460000±n/a nM
Citation
 Stokmaier, D; Khorev, O; Cutting, B; Born, R; Ricklin, D; Ernst, TO; Böni, F; Schwingruber, K; Gentner, M; Wittwer, M; Spreafico, M; Vedani, A; Rabbani, S; Schwardt, O; Ernst, B Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R). Bioorg Med Chem 17:7254-64 (2009) [PubMed]  Article 
Target
Name:
Asialoglycoprotein receptor 1
Synonyms:
ASGP-R 1 | ASGPR 1 | ASGR1 | ASGR1_HUMAN | CLEC4H1 | Hepatic lectin H1
Type:
PROTEIN
Mol. Mass.:
33177.60
Organism:
Homo sapiens (Human)
Description:
ChEMBL_603824
Residue:
291
Sequence:
MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL
  
Inhibitor
Name:
BDBM50077229
Synonyms:
CHEMBL300520 | beta-D-galactopyranose | beta-D-galactose
Type:
Small organic molecule
Emp. Form.:
C6H12O6
Mol. Mass.:
180.1559
SMILES:
OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: