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Target
Asialoglycoprotein receptor 1
Ligand
BDBM50304487
Substrate
n/a
Meas. Tech.
ChEMBL_603824 (CHEMBL1042964)
IC50
1828000±n/a nM
Citation
 Stokmaier, D; Khorev, O; Cutting, B; Born, R; Ricklin, D; Ernst, TO; Böni, F; Schwingruber, K; Gentner, M; Wittwer, M; Spreafico, M; Vedani, A; Rabbani, S; Schwardt, O; Ernst, B Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R). Bioorg Med Chem 17:7254-64 (2009) [PubMed]  Article 
Target
Name:
Asialoglycoprotein receptor 1
Synonyms:
ASGP-R 1 | ASGPR 1 | ASGR1 | ASGR1_HUMAN | CLEC4H1 | Hepatic lectin H1
Type:
PROTEIN
Mol. Mass.:
33177.60
Organism:
Homo sapiens (Human)
Description:
ChEMBL_603824
Residue:
291
Sequence:
MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL
  
Inhibitor
Name:
BDBM50304487
Synonyms:
(2R,3R,4S,5S,6R)-2,3,4,5-tetramethoxy-6-(methoxymethyl)tetrahydro-2H-pyran | CHEMBL595499
Type:
Small organic molecule
Emp. Form.:
C11H22O6
Mol. Mass.:
250.2888
SMILES:
COC[C@H]1O[C@@H](OC)[C@H](OC)[C@@H](OC)[C@H]1OC |r|
Structure:
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