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Target
P2Y purinoceptor 6
Ligand
BDBM50306711
Substrate
n/a
Meas. Tech.
ChEMBL_611870 (CHEMBL1070825)
EC50
140±n/a nM
Citation
 Ginsburg-Shmuel, T; Haas, M; Schumann, M; Reiser, G; Kalid, O; Stern, N; Fischer, B 5-OMe-UDP is a potent and selective P2Y(6)-receptor agonist. J Med Chem 53:1673-85 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6 | P2RY6_HUMAN | P2Y purinoceptor 6 | P2Y6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36452.29
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1511151
Residue:
328
Sequence:
MEWDNGTGQALGLPPTTCVYRENFKQLLLPPVYSAVLAAGLPLNICVITQICTSRRALTRTAVYTLNLALADLLYACSLPLLIYNYAQGDHWPFGDFACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWLVCVAVWLAVTTQCLPTAIFAATGIQRNRTVCYDLSPPALATHYMPYGMALTVIGFLLPFAALLACYCLLACRLCRQDGPAEPVAQERRGKAARMAVVVAAAFAISFLPFHITKTAYLAVRSTPGVPCTVLEAFAAAYKGTRPFASANSVLDPILFYFTQKKFRRRPHELLQKLTAKWQRQGR
  
Inhibitor
Name:
BDBM50306711
Synonyms:
CHEMBL590441 | INS-48823
Type:
Small organic molecule
Emp. Form.:
C26H32N4O23P4
Mol. Mass.:
892.4403
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](C3OC(Cc4ccccc4)OC23)n2ccc(=O)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Structure:
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