Reaction Details Report a problem with these data
Target
P2Y purinoceptor 1
Ligand
BDBM50321583
Substrate
n/a
Meas. Tech.
ChEMBL_639731 (CHEMBL1175620)
Ki
2500±n/a nM
Citation
 Thalji, RK; Aiyar, N; Davenport, EA; Erhardt, JA; Kallal, LA; Morrow, DM; Senadhi, S; Burns-Kurtis, CL; Marino, JP Benzofuran-substituted urea derivatives as novel P2Y(1) receptor antagonists. Bioorg Med Chem Lett 20:4104-7 (2010) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50321583
Synonyms:
1-(4-(trifluoromethoxy)phenyl)-3-(2-(2-(trifluoromethyl)phenyl)benzofuran-7-yl)urea | CHEMBL1172138
Type:
Small organic molecule
Emp. Form.:
C23H14F6N2O3
Mol. Mass.:
480.3593
SMILES:
FC(F)(F)Oc1ccc(NC(=O)Nc2cccc3cc(oc23)-c2ccccc2C(F)(F)F)cc1
Structure:
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