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Target
6-phosphogluconate dehydrogenase, decarboxylating
Ligand
BDBM50148790
Substrate
n/a
Meas. Tech.
ChEMBL_642682 (CHEMBL1176974)
Ki
10790±n/a nM
Citation
 Ruda, GF; Campbell, G; Alibu, VP; Barrett, MP; Brenk, R; Gilbert, IH Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase. Bioorg Med Chem 18:5056-62 (2010) [PubMed]  Article 
Target
Name:
6-phosphogluconate dehydrogenase, decarboxylating
Synonyms:
6PGD_SHEEP | PGD
Type:
PROTEIN
Mol. Mass.:
52976.41
Organism:
Ovis aries
Description:
ChEMBL_642682
Residue:
483
Sequence:
MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVLGAHSLEEMVSKLKKPRRIILLVKAGQAVDNFIEKLVPLLDIGDIIIDGGNSEYRDTMRRCRDLKDKGILFVGSGVSGGEDGARYGPSLMPGGNKEAWPHIKAIFQGIAAKVGTGEPCCDWVGDDGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGLGHKEMAKAFEEWNKTELDSFLIEITASILKFQDADGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQNIPFEGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDDFFKSAVENCQDSWRRAISTGVQAGIPMPCFTTALSFYDGYRHAMLPANLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGSVSSSSYNA
  
Inhibitor
Name:
BDBM50148790
Synonyms:
(2R,3R)-2,3-Dihydroxy-4-phosphonooxy-butyric acid anion
Type:
Small organic molecule
Emp. Form.:
C4H8O8P
Mol. Mass.:
215.0758
SMILES:
O[C@H](COP(O)(O)=O)[C@@H](O)C([O-])=O
Structure:
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