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Target
Galectin-9
Ligand
BDBM50326600
Substrate
n/a
Meas. Tech.
ChEMBL_661838 (CHEMBL1252154)
Kd
1822±n/a nM
Citation
 Salameh, BA; Cumpstey, I; Sundin, A; Leffler, H; Nilsson, UJ 1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors. Bioorg Med Chem 18:5367-78 (2010) [PubMed]  Article 
Target
Name:
Galectin-9
Synonyms:
LEG9_HUMAN | LGALS9
Type:
PROTEIN
Mol. Mass.:
39532.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1454626
Residue:
355
Sequence:
MAFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQNPRTVPVQPAFSTVPFSQPVCFPPRPRGRRQKPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT
  
Inhibitor
Name:
BDBM50326600
Synonyms:
CHEMBL1253217 | Di-(3,5-dimethoxybenzamido)-thiodigalactoside
Type:
Small organic molecule
Emp. Form.:
C30H40N2O14S
Mol. Mass.:
684.709
SMILES:
COc1cc(OC)cc(c1)C(=O)N[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](S[C@H]2O[C@H](CO)[C@H](O)[C@H](NC(=O)c3cc(OC)cc(OC)c3)[C@H]2O)[C@@H]1O |r|
Structure:
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