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Target
Sialidase-3
Ligand
BDBM50331694
Substrate
n/a
Meas. Tech.
ChEMBL_687673 (CHEMBL1291057)
IC50
320000±n/a nM
Citation
 Zou, Y; Albohy, A; Sandbhor, M; Cairo, CW Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid. Bioorg Med Chem Lett 20:7529-33 (2010) [PubMed]  Article 
Target
Name:
Sialidase-3
Synonyms:
NEU3 | NEUR3_HUMAN | Sialidase 3 | Sialidase-3
Type:
PROTEIN
Mol. Mass.:
48257.99
Organism:
Homo sapiens (Human)
Description:
ChEMBL_461856
Residue:
428
Sequence:
MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRRGLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSGRNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYTYYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVLYCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSSKDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRPWILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGRNPSQFKSN
  
Inhibitor
Name:
BDBM50331694
Synonyms:
(2R,3R,4S)-3-acetamido-2-((1R,2R)-3-benzamido-1,2-dihydroxypropyl)-4-hydroxy-3,4-dihydro-2H-pyran-6-carboxylate | CHEMBL1289198
Type:
Small organic molecule
Emp. Form.:
C18H22N2O8
Mol. Mass.:
394.3759
SMILES:
CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CNC(=O)c1ccccc1)C(O)=O |r,c:7|
Structure:
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