Reaction Details Report a problem with these data
Target
Pteridine reductase 1
Ligand
BDBM50335104
Substrate
n/a
Meas. Tech.
ChEMBL_702836 (CHEMBL1655366)
IC50
29000±n/a nM
Citation
 Shi, K; Huang, Q; Huang, Y; Lee, TC; Yu, H Reducing the brittleness of zein films through chemical modification. J Agric Food Chem 59:56-61 (2011) [PubMed]  Article 
Target
Name:
Pteridine reductase 1
Synonyms:
HMTXR | PTR1 | PTR1_LEIMA
Type:
PROTEIN
Mol. Mass.:
30459.34
Organism:
Leishmania major
Description:
ChEMBL_1470027
Residue:
288
Sequence:
MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRFAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
  
Inhibitor
Name:
BDBM50335104
Synonyms:
3-(5-Amino-[1,3,4]thiadiazol-2-yl)-1-(thiophen-2-yl)propan-1-one | CHEMBL1650287
Type:
Small organic molecule
Emp. Form.:
C9H9N3OS2
Mol. Mass.:
239.317
SMILES:
Nc1nnc(CCC(=O)c2cccs2)s1
Structure:
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