Reaction Details Report a problem with these data
Target
Pteridine reductase 1
Ligand
BDBM30705
Substrate
n/a
Meas. Tech.
ChEMBL_702836 (CHEMBL1655366)
IC50
50000±n/a nM
Citation
 Shi, K; Huang, Q; Huang, Y; Lee, TC; Yu, H Reducing the brittleness of zein films through chemical modification. J Agric Food Chem 59:56-61 (2011) [PubMed]  Article 
Target
Name:
Pteridine reductase 1
Synonyms:
HMTXR | PTR1 | PTR1_LEIMA
Type:
PROTEIN
Mol. Mass.:
30459.34
Organism:
Leishmania major
Description:
ChEMBL_1470027
Residue:
288
Sequence:
MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRFAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
  
Inhibitor
Name:
BDBM30705
Synonyms:
CHEMBL744 | MLS000069369 | RILUZOLE | SMR000058231 | cid_5070
Type:
Small organic molecule
Emp. Form.:
C8H5F3N2OS
Mol. Mass.:
234.198
SMILES:
Nc1nc2ccc(OC(F)(F)F)cc2s1
Structure:
Search PDB for entries with ligand similarity: