Reaction Details Report a problem with these data
Target
Pteridine reductase 1
Ligand
BDBM50335101
Substrate
n/a
Meas. Tech.
ChEMBL_702837 (CHEMBL1655367)
Ki
9000±n/a nM
Citation
 Shi, K; Huang, Q; Huang, Y; Lee, TC; Yu, H Reducing the brittleness of zein films through chemical modification. J Agric Food Chem 59:56-61 (2011) [PubMed]  Article 
Target
Name:
Pteridine reductase 1
Synonyms:
HMTXR | PTR1 | PTR1_LEIMA
Type:
PROTEIN
Mol. Mass.:
30459.34
Organism:
Leishmania major
Description:
ChEMBL_1470027
Residue:
288
Sequence:
MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRFAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
  
Inhibitor
Name:
BDBM50335101
Synonyms:
2-(1,3-Dioxoisoindolin-2-yl)-N-5-(1,3-dioxoisoindolin-2-ylmethyl)-[1,3,4]thiadiazol-2-ylacetamide | CHEMBL1650466
Type:
Small organic molecule
Emp. Form.:
C21H13N5O5S
Mol. Mass.:
447.423
SMILES:
O=C(CN1C(=O)c2ccccc2C1=O)Nc1nnc(CN2C(=O)c3ccccc3C2=O)s1
Structure:
Search PDB for entries with ligand similarity: