Reaction Details Report a problem with these data
Target
Pteridine reductase 1
Ligand
BDBM50335102
Substrate
n/a
Meas. Tech.
ChEMBL_702837 (CHEMBL1655367)
Ki
7000±n/a nM
Citation
 Shi, K; Huang, Q; Huang, Y; Lee, TC; Yu, H Reducing the brittleness of zein films through chemical modification. J Agric Food Chem 59:56-61 (2011) [PubMed]  Article 
Target
Name:
Pteridine reductase 1
Synonyms:
HMTXR | PTR1 | PTR1_LEIMA
Type:
PROTEIN
Mol. Mass.:
30459.34
Organism:
Leishmania major
Description:
ChEMBL_1470027
Residue:
288
Sequence:
MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRFAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
  
Inhibitor
Name:
BDBM50335102
Synonyms:
3-Chloro-N-[5-(2-chloroethyl)-[1,3,4]thiadiazol-2-yl]-propionamide | CHEMBL1650465
Type:
Small organic molecule
Emp. Form.:
C7H9Cl2N3OS
Mol. Mass.:
254.137
SMILES:
ClCCC(=O)Nc1nnc(CCCl)s1
Structure:
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