Reaction Details Report a problem with these data
Target
Deoxyribonuclease-1
Ligand
BDBM50379292
Substrate
n/a
Meas. Tech.
ChEMBL_811427 (CHEMBL2013685)
IC50
>200000±n/a nM
Citation
 Myobatake, Y; Takeuchi, T; Kuramochi, K; Kuriyama, I; Ishido, T; Hirano, K; Sugawara, F; Yoshida, H; Mizushina, Y Pinophilins A and B, inhibitors of mammalian A-, B-, and Y-family DNA polymerases and human cancer cell proliferation. J Nat Prod 75:135-41 (2012) [PubMed]  Article 
Target
Name:
Deoxyribonuclease-1
Synonyms:
DNAS1_BOVIN | DNASE1 | DNL1
Type:
PROTEIN
Mol. Mass.:
31341.11
Organism:
Bos taurus
Description:
ChEMBL_1297301
Residue:
282
Sequence:
MRGTRLMGLLLALAGLLQLGLSLKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
  
Inhibitor
Name:
BDBM50379292
Synonyms:
CHEMBL2011646
Type:
Small organic molecule
Emp. Form.:
C21H22O7
Mol. Mass.:
386.3952
SMILES:
C\C=C\C1=CC2=CC(=O)[C@@](C)(OC(=O)c3c(C)cc(O)cc3O)[C@@H](O)[C@@H]2CO1 |r,t:3,5|
Structure:
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