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Target
Deoxyribonuclease-1
Ligand
BDBM50379294
Substrate
n/a
Meas. Tech.
ChEMBL_811427 (CHEMBL2013685)
IC50
>200000±n/a nM
Citation
 Myobatake, Y; Takeuchi, T; Kuramochi, K; Kuriyama, I; Ishido, T; Hirano, K; Sugawara, F; Yoshida, H; Mizushina, Y Pinophilins A and B, inhibitors of mammalian A-, B-, and Y-family DNA polymerases and human cancer cell proliferation. J Nat Prod 75:135-41 (2012) [PubMed]  Article 
Target
Name:
Deoxyribonuclease-1
Synonyms:
DNAS1_BOVIN | DNASE1 | DNL1
Type:
PROTEIN
Mol. Mass.:
31341.11
Organism:
Bos taurus
Description:
ChEMBL_1297301
Residue:
282
Sequence:
MRGTRLMGLLLALAGLLQLGLSLKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQEVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYDDGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKWHLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAGSLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
  
Inhibitor
Name:
BDBM50379294
Synonyms:
CHEMBL2011647
Type:
Small organic molecule
Emp. Form.:
C21H22O8
Mol. Mass.:
402.3946
SMILES:
Cc1cc(O)cc(O)c1C(=O)O[C@H]1[C@@H]2COC(\C=C\CO)=CC2=CC(=O)[C@@]1(C)O |r,c:21,24|
Structure:
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