Reaction Details Report a problem with these data
Target
Fructose-bisphosphate aldolase, glycosomal
Ligand
BDBM50380325
Substrate
n/a
Meas. Tech.
ChEMBL_813853 (CHEMBL2020222)
IC50
117000±n/a nM
Citation
 Mabiala-Bassiloua, CG; Arthus-Cartier, G; Hannaert, V; Thérisod, H; Sygusch, J; Thérisod, M Mannitol Bis-phosphate Based Inhibitors of Fructose 1,6-Bisphosphate Aldolases. ACS Med Chem Lett 2:804-808 (2011) [PubMed]  Article 
Target
Name:
Fructose-bisphosphate aldolase, glycosomal
Synonyms:
ALD | ALF_TRYBB | Fructose-bisphosphate aldoloase, glycosomal
Type:
PROTEIN
Mol. Mass.:
41192.02
Organism:
Trypanosoma brucei brucei
Description:
ChEMBL_813853
Residue:
372
Sequence:
MSKRVEVLLTQLPAYNRLKTPYEAELIETAKKMTAPGKGLLAADESTGSCSKRFAGIGLSNTAEHRRQYRALMLECEGFEQYISGVILHDETVYQKAKTGETFPQYLRRRGVVPGIKTDCGLEPLVEGAKGEQMTAGLDGYIKRAKKYYAMGCRFCKWRNVYKIQNGTVSEAVVRFNAETLARYAILSQLCGLVPIVEPEVMIDGTHDIETCQRVSQHVWSEVVSALHRHGVVWEGCLLKPNMVVPGAESGLKGHAEQVAEYTVKTLARVIPPALPGVTFLSGGLSEVMASEYLNAMNNCPLPRPWKLTFSYARALQSSAIKRWGGKESGVEAGRRAFMHRAKMNSLAQLGKYNRADDDKDSQSLYVAGNTY
  
Inhibitor
Name:
BDBM50380325
Synonyms:
CHEMBL2017787
Type:
Small organic molecule
Emp. Form.:
C11H26O12P2
Mol. Mass.:
412.2645
SMILES:
CCCCCO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O |r|
Structure:
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