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Target
Acrosin
Ligand
BDBM50354886
Substrate
n/a
Meas. Tech.
ChEMBL_815401 (CHEMBL2027053)
IC50
142600000±n/a nM
Citation
 Liu, X; Chen, Q; Zhu, J; Fan, Y; Ding, L; Zhao, J; Han, G; Tian, W; Qi, J; Zhou, Y; Lv, J Synthesis and acrosin inhibitory activity of methyl 5-substituted-1H-benzo[d]imidazol-2-yl carbamate derivatives. Bioorg Med Chem Lett 22:3554-9 (2012) [PubMed]  Article 
Target
Name:
Acrosin
Synonyms:
ACR | ACRO_HUMAN | ACRS
Type:
PROTEIN
Mol. Mass.:
45865.48
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1365286
Residue:
421
Sequence:
MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRMIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASPLPPPPPPPPPTPSSTTKLPQGLSFAKRLQQLIEVLKGKTYSDGKNHYDMETTELPELTSTS
  
Inhibitor
Name:
BDBM50354886
Synonyms:
CHEMBL466465
Type:
Small organic molecule
Emp. Form.:
C14H21ClN2O3S
Mol. Mass.:
332.846
SMILES:
Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl |r|
Structure:
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