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Target
Sialidase-2
Ligand
BDBM50382736
Substrate
n/a
Meas. Tech.
ChEMBL_815224 (CHEMBL2025415)
Ki
20000000±n/a nM
Citation
 Kai, H; Hinou, H; Nishimura, S Aglycone-focused randomization of 2-difluoromethylphenyl-type sialoside suicide substrates for neuraminidases. Bioorg Med Chem 20:2739-46 (2012) [PubMed]  Article 
Target
Name:
Sialidase-2
Synonyms:
Cytosolic sialidase | N-acetyl-alpha-neuraminidase 2 | NEU2 | NEUR2_HUMAN | Sialidase 2 | Sialidase-2
Type:
PROTEIN
Mol. Mass.:
42256.20
Organism:
Homo sapiens (Human)
Description:
ChEMBL_960638
Residue:
380
Sequence:
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEYLPQ
  
Inhibitor
Name:
BDBM50382736
Synonyms:
CHEMBL2022772
Type:
Small organic molecule
Emp. Form.:
C18H22F2N4O9
Mol. Mass.:
476.3855
SMILES:
CC(=O)N[C@@H]1[C@@H](O)C[C@@](Oc2ccc(cc2C(F)F)N=[N+]=[N-])(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O |r|
Structure:
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