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Target
G-protein coupled receptor 35
Ligand
BDBM4350
Substrate
n/a
Meas. Tech.
ChEMBL_821044 (CHEMBL2039370)
EC50
9800±n/a nM
Citation
 Deng, H; Hu, H; Ling, S; Ferrie, AM; Fang, Y Discovery of Natural Phenols as G Protein-Coupled Receptor-35 (GPR35) Agonists. ACS Med Chem Lett 3:165-169 (2012) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM4350
Synonyms:
(2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid | benzylidenemalononitrile (BMN) deriv. 34
Type:
Small organic molecule
Emp. Form.:
C10H7NO3
Mol. Mass.:
189.1675
SMILES:
OC(=O)C(=C\c1ccc(O)cc1)\C#N
Structure:
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