Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM50385235
Substrate
n/a
Meas. Tech.
ChEMBL_822345 (CHEMBL2038723)
EC50
950±n/a nM
Citation
 Deng, H; Hu, J; Hu, H; He, M; Fang, Y Thieno[3,2-b]thiophene-2-carboxylic acid derivatives as GPR35 agonists. Bioorg Med Chem Lett 22:4148-52 (2012) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM50385235
Synonyms:
CHEMBL2037461
Type:
Small organic molecule
Emp. Form.:
C11H10O2S2
Mol. Mass.:
238.326
SMILES:
Cc1c(sc2c(csc12)C1CC1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: