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Target
Membrane-bound lytic murein transglycosylase B
Ligand
BDBM50386413
Substrate
n/a
Meas. Tech.
ChEMBL_826832 (CHEMBL2051549)
Kd
1000000±n/a nM
Citation
 Yamaguchi, T; Blázquez, B; Hesek, D; Lee, M; Llarrull, LI; Boggess, B; Oliver, AG; Fisher, JF; Mobashery, S Inhibitors for Bacterial Cell-Wall Recycling. ACS Med Chem Lett 3:238-242 (2012) [PubMed]  Article 
Target
Name:
Membrane-bound lytic murein transglycosylase B
Synonyms:
35 kDa soluble lytic transglycosylase | 4.2.2.n1 | JW2671 | MLTB_ECOLI | Murein hydrolase B | Slt35 | mltB
Type:
PROTEIN
Mol. Mass.:
40263.83
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_826832
Residue:
361
Sequence:
MFKRRYVTLLPLFVLLAACSSKPKPTETDTTTGTPSGGFLLEPQHNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTTSVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIGVETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFAGAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMANGQAPGLPNGFKTKYSISQLAAAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYTITRYNHSTHYAMAVWQLGQAVALARVQ
  
Inhibitor
Name:
BDBM50386413
Synonyms:
CHEMBL2047303
Type:
Small organic molecule
Emp. Form.:
C11H20N2O6
Mol. Mass.:
276.2863
SMILES:
C[C@@H](O[C@@H]1[C@H](CN[C@H](CO)[C@H]1O)NC(C)=O)C(O)=O |r|
Structure:
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