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Target
Isocitrate lyase
Ligand
BDBM50386865
Substrate
n/a
Meas. Tech.
ChEMBL_827404 (CHEMBL2051074)
IC50
50200±n/a nM
Citation
 Won, TH; Jeon, JE; Lee, SH; Rho, BJ; Oh, KB; Shin, J Beta-carboline alkaloids derived from the ascidian Synoicum sp. Bioorg Med Chem 20:4082-7 (2012) [PubMed]  Article 
Target
Name:
Isocitrate lyase
Synonyms:
ACEA_CANAX | ICL1
Type:
PROTEIN
Mol. Mass.:
61398.95
Organism:
Candida albicans
Description:
ChEMBL_972063
Residue:
550
Sequence:
MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQADKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLADYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGITAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGSNLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIESEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGKDIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKAAVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSNQYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTEDQFKESKAKA
  
Inhibitor
Name:
BDBM50386865
Synonyms:
CHEMBL2048337
Type:
Small organic molecule
Emp. Form.:
C18H11BrN2O2
Mol. Mass.:
367.196
SMILES:
Oc1ccc(cc1)C(=O)c1nccc2c3cc(Br)ccc3[nH]c12
Structure:
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