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TargetDehydrosqualene synthase
LigandBDBM50388398
Substrate/Competitorn/a
Meas. Tech.ChEMBL_829914
Ki 360±n/a nM
Citation Lin, FYLiu, YLLi, KCao, RZhu, WAxelson, JPang, ROldfield, E Head-to-head prenyl tranferases: anti-infective drug targets. J Med Chem55:4367-72 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dehydrosqualene synthase
Name:Dehydrosqualene synthase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:34309.10
Organism:Staphylococcus aureus
Description:ChEMBL_1352846
Residue:287
Sequence:
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFL
NQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMF
ETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENE
RIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPI
IELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKYHRI
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  Blast E-value cutoff:
BDBM50388398
NameBDBM50388398
Synonyms:CHEMBL561057 | SQ-109
TypeSmall organic molecule
Emp. Form.C22H38N2
Mol. Mass.330.5505
SMILESCC(C)=CCC\C(C)=C\CNCCNC1C2CC3CC(C2)CC1C3 |TLB:18:19:16.17.23:14,23:22:20:16.17.18,13:14:20:16.17.18,13:14:16.17.23:20.19.21,THB:18:17:14:20.19.21,23:17:20:22.14.21,21:19:16:23.22.14,21:22:16:20.18.19,13:14:16:20.18.19,(-5.14,2.27,;-5.13,1.44,;-5.84,1.02,;-4.41,1.04,;-3.7,1.46,;-2.98,1.06,;-2.28,1.48,;-2.29,2.3,;-1.56,1.08,;-.85,1.5,;-.13,1.09,;.58,1.51,;1.3,1.11,;2.04,1.48,;2.72,1.02,;2.74,.22,;2.11,-.47,;2.91,-.24,;3.67,-.52,;4.2,.17,;3.46,-.03,;4.19,.99,;3.44,1.28,;2.89,.61,)|
Structure
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