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Target
Calcium/calmodulin-dependent protein kinase type II subunit beta
Ligand
BDBM50388936
Substrate
n/a
Meas. Tech.
ChEMBL_830767 (CHEMBL2065182)
IC50
25900±n/a nM
Citation
 Wang, RE; Hunt, CR; Chen, J; Taylor, JS Biotinylated quercetin as an intrinsic photoaffinity proteomics probe for the identification of quercetin target proteins. Bioorg Med Chem 19:4710-20 (2011) [PubMed]  Article 
Target
Name:
Calcium/calmodulin-dependent protein kinase type II subunit beta
Synonyms:
CAM2 | CAMK2 | CAMK2B | CAMKB | CaM kinase II | CaM kinase II beta | CaM kinase II subunit beta | CaM-kinase II beta chain | CaMK-II subunit beta | Calcium/calmodulin-dependent protein kinase type II | Calcium/calmodulin-dependent protein kinase type II beta chain | KCC2B_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
72685.48
Organism:
Homo sapiens (Human)
Description:
gi_26051204
Residue:
666
Sequence:
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSVRRGSGAPEAEGPLPCPSPAPFSPLPAPSPRISDILNSVRRGSGTPEAEGPLSAGPPPCLSPALLGPLSSPSPRISDILNSVRRGSGTPEAEGPSPVGPPPCPSPTIPGPLPTPSRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ
  
Inhibitor
Name:
BDBM50388936
Synonyms:
CHEMBL2063416
Type:
Small organic molecule
Emp. Form.:
C33H40N4O12S
Mol. Mass.:
716.755
SMILES:
Oc1ccc(cc1O)-c1oc2cc(OCC(=O)NCCOCCOCCNC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@H]34)cc(O)c2c(=O)c1O |r|
Structure:
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