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TargetKallikrein 7
LigandBDBM50391078
Substrate/Competitorn/a
Meas. Tech.ChEMBL_840620
IC50 16300±n/a nM
Citation Freitas, RFTeixeira, TSBarros, TGSantos, JAKondo, MYJuliano, MAJuliano, LBlaber, MAntunes, OAAbrahão, OPinheiro, SMuri, EMPuzer, L Isomannide derivatives as new class of inhibitors for human kallikrein 7. Bioorg Med Chem Lett22:6072-5 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kallikrein 7
Name:Kallikrein 7
Synonyms:Kallikrein-7 | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:PROTEIN
Mol. Mass.:27535.05
Organism:Homo sapiens
Description:ChEMBL_1469257
Residue:253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50391078
NameBDBM50391078
Synonyms:CHEMBL2087346
TypeSmall organic molecule
Emp. Form.C27H26N2O6
Mol. Mass.474.5051
SMILESO=C(N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1ccco1 |r|
Structure
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n/a