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TargetKallikrein 5
LigandBDBM50391077
Substrate/Competitorn/a
Meas. Tech.ChEMBL_840623
Ki 200000±n/a nM
Citation Freitas, RFTeixeira, TSBarros, TGSantos, JAKondo, MYJuliano, MAJuliano, LBlaber, MAntunes, OAAbrahão, OPinheiro, SMuri, EMPuzer, L Isomannide derivatives as new class of inhibitors for human kallikrein 7. Bioorg Med Chem Lett22:6072-5 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kallikrein 5
Name:Kallikrein 5
Synonyms:KLK-L2 | Kallikrein-5 | Kallikrein-like protein 2 | Stratum corneum tryptic enzyme
Type:PROTEIN
Mol. Mass.:32031.75
Organism:Homo sapiens
Description:ChEMBL_1282456
Residue:293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNNLMLIKLNRRIRPTKDVRPINVSSHCPS
AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50391077
NameBDBM50391077
Synonyms:CHEMBL2087345
TypeSmall organic molecule
Emp. Form.C28H27N3O5
Mol. Mass.485.5311
SMILESO=C(N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1cccnc1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a