Reaction Details Report a problem with these data
Target
4-aminobutyrate aminotransferase, mitochondrial
Ligand
BDBM50391515
Substrate
n/a
Meas. Tech.
ChEMBL_849664 (CHEMBL2150218)
Ki
2490000±n/a nM
Citation
 Hawker, DD; Silverman, RB Synthesis and evaluation of novel heteroaromatic substrates of GABA aminotransferase. Bioorg Med Chem 20:5763-73 (2012) [PubMed]  Article 
Target
Name:
4-aminobutyrate aminotransferase, mitochondrial
Synonyms:
(S)-3-amino-2-methylpropionate transaminase | 2.6.1.19 | 2.6.1.22 | 4-aminobutyrate aminotransferase, mitochondrial | ABAT | GABA aminotransferase | GABA transaminase | GABA-AT | GABA-T | GABAT | GABT_PIG | Gamma-amino-N-butyrate transaminase | L-AIBAT
Type:
n/a
Mol. Mass.:
56633.06
Organism:
Sus scrofa
Description:
n/a
Residue:
500
Sequence:
MASVLLTRRLACSFRHNHRLLVPGWRHISQAAAKVDVEFDYDGPLMKTEVPGPRSRELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSIPIGYSHPALVKLVQQPQNVSTFINRPALGILPPENFVEKLRESLLSVAPKGMSQLITMACGSCSNENAFKTIFMWYRSKERGQSAFSKEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDISRKHGCAFLVDEVQTGGGSTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLSNAAHAGKVLLTGLLDLQARYPQFISRVRGRGTFCSFDTPDESIRNKLISIARNKGVMLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK
  
Inhibitor
Name:
BDBM50391515
Synonyms:
CHEMBL2147348
Type:
Small organic molecule
Emp. Form.:
C6H7NO2S
Mol. Mass.:
157.19
SMILES:
NCc1ccc(s1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: