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Target
Cathepsin B
Ligand
BDBM50391541
Substrate
n/a
Meas. Tech.
ChEMBL_849825 (CHEMBL2148452)
EC50
700±n/a nM
Citation
 Anas, AR; Kisugi, T; Umezawa, T; Matsuda, F; Campitelli, MR; Quinn, RJ; Okino, T Thrombin inhibitors from the freshwater cyanobacterium Anabaena compacta. J Nat Prod 75:1546-52 (2012) [PubMed]  Article 
Target
Name:
Cathepsin B
Synonyms:
APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1
Type:
Enzyme
Mol. Mass.:
37819.69
Organism:
Homo sapiens (Human)
Description:
gi_63102437
Residue:
339
Sequence:
MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
  
Inhibitor
Name:
BDBM50391541
Synonyms:
CHEMBL2147467
Type:
Small organic molecule
Emp. Form.:
C32H44N4O8
Mol. Mass.:
612.7138
SMILES:
C[C@H]1C[C@H](N(C1)C(=O)[C@@H](CCc1ccc(O)cc1)NC(=O)[C@H](O)Cc1ccc(O)cc1)C(=O)N(C)[C@H](CCCCN)C(O)=O |r|
Structure:
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