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Target
D-amino-acid oxidase
Ligand
BDBM50393070
Substrate
n/a
Meas. Tech.
ChEMBL_853596 (CHEMBL2154051)
IC50
700±n/a nM
Citation
 Berry, JF; Ferraris, DV; Duvall, B; Hin, N; Rais, R; Alt, J; Thomas, AG; Rojas, C; Hashimoto, K; Slusher, BS; Tsukamoto, T Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase. ACS Med Chem Lett 3:839-843 (2012) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-Amino Acid Oxidase (DAAO) | D-amino-acid oxidase (DAAO) | DAMOX | DAO | OXDA_PIG
Type:
Flavoprotein
Mol. Mass.:
39338.01
Organism:
Sus scrofa (pig)
Description:
Homodimer.
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGGTFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL
  
Inhibitor
Name:
BDBM50393070
Synonyms:
CHEMBL2152731
Type:
Small organic molecule
Emp. Form.:
C8H7FN2O2
Mol. Mass.:
182.1518
SMILES:
Cc1c(F)ccc2n(O)c(=O)[nH]c12
Structure:
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