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TargetT-cell surface antigen CD2
LigandBDBM50393200
Substrate/Competitorn/a
Meas. Tech.ChEMBL_850654
IC50 9.4±n/a nM
Citation Gokhale, AWeldeghiorghis, TKTaneja, VSatyanarayanajois, SD Conformationally constrained peptides from CD2 to modulate protein-protein interactions between CD2 and CD58. J Med Chem54:5307-19 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
T-cell surface antigen CD2
Name:T-cell surface antigen CD2
Synonyms:CD_antigen=CD2 | Erythrocyte receptor | LFA-2 | LFA-3 receptor | Rosette receptor | T-cell surface antigen T11/Leu-5
Type:PROTEIN
Mol. Mass.:39473.97
Organism:Homo sapiens (Human)
Description:ChEMBL_850654
Residue:351
Sequence:
MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWE
KTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEK
IFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSL
SAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQ
RSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPP
GHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50393200
NameBDBM50393200
Synonyms:CHEMBL2153727
TypeSmall organic molecule
Emp. Form.C52H77N11O18
Mol. Mass.1144.2307
SMILESCC[C@H](C)[C@@H]1NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H]2CCCN2C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC1=O)[C@@H](C)CC |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
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