Reaction Details Report a problem with these data
Target
P2X purinoceptor 1
Ligand
BDBM50399172
Substrate
n/a
Meas. Tech.
ChEMBL_876874 (CHEMBL2184468)
IC50
2020±n/a nM
Citation
 Hernandez-Olmos, V; Abdelrahman, A; El-Tayeb, A; Freudendahl, D; Weinhausen, S; Müller, CE N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem 55:9576-88 (2012) [PubMed]  Article 
Target
Name:
P2X purinoceptor 1
Synonyms:
ATP receptor | P2RX1 | P2RX1_HUMAN | P2X1 | Purinergic receptor | Purinergic, P2X
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44992.65
Organism:
Homo sapiens (Human)
Description:
Purinergic, P2X 0 HUMAN::P51575
Residue:
399
Sequence:
MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSGLISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHPEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVENGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
  
Inhibitor
Name:
BDBM50399172
Synonyms:
CHEMBL2180174
Type:
Small organic molecule
Emp. Form.:
C19H22N2O2
Mol. Mass.:
310.3902
SMILES:
CCCN(CCC)C(=O)N1c2ccccc2Oc2ccccc12
Structure:
Search PDB for entries with ligand similarity: