Reaction Details Report a problem with these data
Target
P2X purinoceptor 4
Ligand
BDBM50399165
Substrate
n/a
Meas. Tech.
ChEMBL_876875 (CHEMBL2184469)
IC50
1770±n/a nM
Citation
 Hernandez-Olmos, V; Abdelrahman, A; El-Tayeb, A; Freudendahl, D; Weinhausen, S; Müller, CE N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem 55:9576-88 (2012) [PubMed]  Article 
Target
Name:
P2X purinoceptor 4
Synonyms:
ATP receptor | P2RX4_MOUSE | P2rx4 | P2x4 | Purinergic receptor
Type:
PROTEIN
Mol. Mass.:
43443.55
Organism:
Mus musculus
Description:
ChEMBL_1283887
Residue:
388
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRVVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVVPAQEENSLFIMTNMIVTVNQTQGTCPEIPDKTSICDSDANCTLGSSDTHSSGIGTGRCVPFNASVKTCEVAAWCPVENDAGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNARTDPFCPIFRLGQIVADAGHSFQEMAVEGGIMGIQIKWDCNLDRAASHCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGNEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKRYYYRDKKYKYVEDYEQGLSGEMNQ
  
Inhibitor
Name:
BDBM50399165
Synonyms:
CHEMBL2180137
Type:
Small organic molecule
Emp. Form.:
C20H15NO3
Mol. Mass.:
317.338
SMILES:
O=C(OCc1ccccc1)N1c2ccccc2Oc2ccccc12
Structure:
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