Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50402141
Substrate
n/a
Meas. Tech.
ChEMBL_884722 (CHEMBL2215603)
Ki
70.7±n/a nM
Citation
 Fujii, H; Nakajima, R; Akiyama, J; Yamamoto, N; Hirayama, S; Nemoto, T; Gouda, H; Hirono, S; Nagase, H Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: part 3, novel propellane derivatives with pentacyclic skeletons. Bioorg Med Chem Lett 22:7697-701 (2012) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50402141
Synonyms:
CHEMBL2207681
Type:
Small organic molecule
Emp. Form.:
C22H27NO3
Mol. Mass.:
353.4547
SMILES:
O[C@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 |r|
Structure:
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