Reaction Details Report a problem with these data
Target
Angiogenin
Ligand
BDBM50402338
Substrate
n/a
Meas. Tech.
ChEMBL_885935 (CHEMBL2215697)
Ki
360000±n/a nM
Citation
 Parmenopoulou, V; Chatzileontiadou, DS; Manta, S; Bougiatioti, S; Maragozidis, P; Gkaragkouni, DN; Kaffesaki, E; Kantsadi, AL; Skamnaki, VT; Zographos, SE; Zounpoulakis, P; Balatsos, NA; Komiotis, D; Leonidas, DD Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg Med Chem 20:7184-93 (2012) [PubMed]  Article 
Target
Name:
Angiogenin
Synonyms:
ANG | ANGI_HUMAN | RNASE5
Type:
Protein
Mol. Mass.:
16563.00
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
147
Sequence:
MVMGLGVLLLVFVLGLGLTPPTLAQDNSRYTHFLTQHYDAKPQGRDDRYCESIMRRRGLTSPCKDINTFIHGNKRSIKAICENKNGNPHRENLRISKSSFQVTTCKLHGGSPWPPCQYRATAGFRNVVVACENGLPVHLDQSIFRRP
  
Inhibitor
Name:
BDBM50402338
Synonyms:
CHEMBL401150
Type:
Small organic molecule
Emp. Form.:
C19H27N7O20P4
Mol. Mass.:
797.3476
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)O[C@H]2C[C@@H](O[C@@H]2COP(O)(O)=O)n2ccc(=O)[nH]c2=O)[C@@H](OP(O)(O)=O)[C@H]1O |r|
Structure:
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