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Target
5-hydroxytryptamine receptor 4
Ligand
BDBM50403163
Substrate
n/a
Meas. Tech.
ChEBML_3321
EC50
9.8±n/a nM
Citation
 Baxter, G; Boyland, P; Gaster, L; King, F Quaternised renzapride as a potent and selective 5-HT4 receptor agonist Bioorg Med Chem Lett 3:633-634 (1993)    Article 
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46117.31
Organism:
RAT
Description:
5-HT4 HTR4 RAT::Q62758
Residue:
406
Sequence:
MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSNSTFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
  
Inhibitor
Name:
BDBM50403163
Synonyms:
OXITRIPTAN
Type:
Small organic molecule
Emp. Form.:
C11H12N2O3
Mol. Mass.:
220.2246
SMILES:
N[C@@H](Cc1c[nH]c2ccc(O)cc12)C(O)=O
Structure:
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