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Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50403196
Substrate
n/a
Meas. Tech.
ChEMBL_98641 (CHEMBL708866)
Kd
4.0±n/a nM
Citation
 Abram, T; Boshagen, H; Butler, J; Cuthbert, N; Francis, H; Gardiner, P; Hartwig, W; Kluender, H; Norman, P; Meier, H; Rosentreter, U; Schlemmer, K; Tudhope, S; Taylor, W A new structural analogue antagonist of peptido-leukotrienes. The discovery of bay x7195 Bioorg Med Chem Lett 3:1517-1522 (1993)    Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50403196
Synonyms:
CHEMBL289880
Type:
Small organic molecule
Emp. Form.:
C30H32O6S
Mol. Mass.:
520.636
SMILES:
OC(=O)CCC(Sc1ccc(cc1)C(O)=O)\C=C\Cc1ccc(OCCCCOc2ccccc2)cc1
Structure:
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