Reaction Details Report a problem with these data
Target
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Ligand
BDBM50403325
Substrate
n/a
Meas. Tech.
ChEBML_204885
Ki
1900±n/a nM
Citation
 Abell, AD; Brandt, M; Levy, MA; Holt, DA A non-steroidal diene acid inhibitor of human type 2 stereoid 5-reductase Bioorg Med Chem Lett 4:2327-2330 (1994)    Article 
Target
Name:
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Synonyms:
3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 5α-Reductase 1 (5α-R1) | S5A1_HUMAN | S5AR | SR type 1 | SRD5A1 | Steroid 5-alpha-reductase | Steroid 5-alpha-reductase 1
Type:
Enzyme
Mol. Mass.:
29472.80
Organism:
Homo sapiens (Human)
Description:
P18405
Residue:
259
Sequence:
MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF
  
Inhibitor
Name:
BDBM50403325
Synonyms:
CHEMBL76998
Type:
Small organic molecule
Emp. Form.:
C15H16ClO2P
Mol. Mass.:
294.713
SMILES:
CC12CCC(=CC1=CCc1cc(Cl)ccc21)P(O)O |c:4,7|
Structure:
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