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Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50403494
Substrate
n/a
Meas. Tech.
ChEBML_1629
IC50
4±n/a nM
Citation
 Lommen, GV; De Bruyn, M; Schroven, M; Verschueren, W; Janssens, W; Verrelst, J; Leysen, J The discovery of a series of new non-indole 5HT1D agonists Bioorg Med Chem Lett 5:2649-2654 (1995)    Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41920.63
Organism:
Homo sapiens (Human)
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:
377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS
  
Inhibitor
Name:
BDBM50403494
Synonyms:
CHEMBL91123
Type:
Small organic molecule
Emp. Form.:
C18H27N3O
Mol. Mass.:
301.4265
SMILES:
C(CNCC1CCc2ccccc2O1)CNC1=NCCCC1 |t:18|
Structure:
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