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TargetInosine-5'-monophosphate dehydrogenase
LigandBDBM50367007
Substrate/Competitorn/a
Meas. Tech.ChEMBL_89668
Ki 54000±n/a nM
Citation Skibo, EBMeyer, RB Inhibition of inosinic acid dehydrogenase by 8-substituted purine nucleotides. J Med Chem24:1155-61 (1982) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Inosine-5'-monophosphate dehydrogenase
Name:Inosine-5'-monophosphate dehydrogenase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:52020.85
Organism:Escherichia coli (strain K12)
Description:ChEMBL_89670
Residue:488
Sequence:
MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIA
LAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAG
YPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRV
EKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAA
GVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIG
PGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMV
GSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGR
VAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKAEFVRISGAGIQESHVHDVTITKE
SPNYRLGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50367007
NameBDBM50367007
Synonyms:CHEMBL605641
TypeSmall organic molecule
Emp. Form.C18H20N5O10PS
Mol. Mass.529.418
SMILESOC1C(COP(O)(O)=O)OC(C1O)n1c(SCCc2ccc(cc2)[N+]([O-])=O)nc2c1nc[n-]c2=[OH+]
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a