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TargetInosine-5'-monophosphate dehydrogenase
LigandBDBM50367018
Substrate/Competitorn/a
Meas. Tech.ChEMBL_89668
Ki 52000±n/a nM
Citation Skibo, EBMeyer, RB Inhibition of inosinic acid dehydrogenase by 8-substituted purine nucleotides. J Med Chem24:1155-61 (1982) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Inosine-5'-monophosphate dehydrogenase
Name:Inosine-5'-monophosphate dehydrogenase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:52020.85
Organism:Escherichia coli (strain K12)
Description:ChEMBL_89670
Residue:488
Sequence:
MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIA
LAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAG
YPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRV
EKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRLRVGAAVGAGAGNEERVDALVAA
GVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKVGIG
PGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMV
GSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGR
VAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKAEFVRISGAGIQESHVHDVTITKE
SPNYRLGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50367018
NameBDBM50367018
Synonyms:CHEMBL605640
TypeSmall organic molecule
Emp. Form.C17H19N6O9PS
Mol. Mass.514.406
SMILESNc1ncnc2n(C3OC(CO[P+](O)(O)[O-])C(O)C3O)c(SCc3ccc(cc3)[N+]([O-])=O)nc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a