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Target
Spermidine synthase
Ligand
BDBM50404650
Substrate
n/a
Meas. Tech.
ChEMBL_201181 (CHEMBL801427)
IC50
80000±n/a nM
Citation
 Tang, KC; Mariuza, R; Coward, JK Synthesis and evaluation of some stable multisubstrate adducts as specific inhibitors of spermidine synthase. J Med Chem 24:1277-84 (1982) [PubMed]  Article 
Target
Name:
Spermidine synthase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
33991.53
Organism:
Rattus norvegicus
Description:
ChEMBL_201181
Residue:
302
Sequence:
MEPGPDGPAAPGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIEVSKKFLPGMAVGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGILCCQGECQWLHLDLIKEMRHFCKSLFPVVSYAYCTIPTYPSGQIGFMLCSKNPSTNFREPVQQLTQAQVEQMQLKYYNSDMHRAAFVLPEFTRKALNDIS
  
Inhibitor
Name:
BDBM50404650
Synonyms:
CHEMBL557606
Type:
Small organic molecule
Emp. Form.:
C19H34N7O3S
Mol. Mass.:
440.583
SMILES:
C[S+](C[C@H]1O[C@@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(CCN)CCCCCN |r|
Structure:
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