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Target
Beta-1 adrenergic receptor
Ligand
BDBM50404804
Substrate
n/a
Meas. Tech.
ChEMBL_37082 (CHEMBL650923)
Kd
1.6±n/a nM
Citation
 Erhardt, PW; Woo, CM; Anderson, WG; Gorczynski, RJ Ultra-short-acting beta-adrenergic receptor blocking agents. 2. (Aryloxy)propanolamines containing esters on the aryl function. J Med Chem 25:1408-12 (1983) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50404804
Synonyms:
CHEMBL13365
Type:
Small organic molecule
Emp. Form.:
C15H23NO4
Mol. Mass.:
281.3474
SMILES:
COC(=O)c1ccccc1OCC(O)CNC(C)(C)C
Structure:
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